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SFC Columns

YMC offers chiral and achiral phases for supercritical fluid chromatography (SFC) applications to provide the chemist with a number of options for SFC separations. SFC can offer some advantages over HPLC for similar applications. The low viscosity of supercritical carbon dioxide allows for analytical separations 3-5 times faster than those for normal phase HPLC. Speed of the SFC separations, conservation of organic solvents, and more concentrated product fractions make SFC a desirable preparative chromatographic technique for purifying chemical mixtures. YMC’s columns are 100% compatible with SFC conditions. Further, Alcyon SFC columns are available, which are specifically packed in a SFC compatible hardware and are tested under SFC conditions.

BioPro HIC HT

HIC Columns for High Throughput Analyses
Ideal drug-to-antibody ratio (DAR) analysis due to novel surface chemistry
High throughput by reducing analysis time
Excellent batch-to-batch reproducibility

Biocompatible YMC-Triart metal-free

Inert columns for bio separations and coordinating compounds
Excellent peak shapes and high sensitivity
Reproducible results day-after-day
No carry-over effects
Ideal for highly sensitive LC/MS analyses
High pressure limits
Ideal choice for Sensitive proteins or peptides, Nucleotides, oligonucleotides, Metal coordinating compounds

Application Specific HPLC Columns

Designed for key pharmaceutical and environmental applications, these columns utilize novel and unique chemistries to provide superior resolution with ease of use.

Size Exclusion HPLC Columns

Want high resolution separation of water-soluble polymers? Our size exclusion columns (SEC) are available in tailored pore sizes to cover a broad range of molecular weight.

Ligand Exchange HPLC Columns

Need a column to separate carbohydrates using dilute acid mobile phase? These polymeric ligand exchange columns utilize a range of counter ions to deliver selectivity required.

Ion Exchange HPLC Columns

Are your analytes ionizable or charged in solution? Our silica-based ion exchange columns are ideal for smaller water-soluble compounds.

Mixed-Mode HPLC Columns

Want to separate ionic and hydrophobic analytes in a single run? The multi-functionality of these columns can eliminate column switching, ion paring, or using columns in series.

Amide HILIC HPLC Columns

Need a HILIC column for very polar analytes? These columns are well suited for separating hydrophilic molecules, including carbohydrates, glycans, and peptides.

HILIC HPLC Columns

Have difficulty retaining polar hydrophilic compounds by RP chromatography? These columns strongly retain compounds that are unretained by conventional reversed phase, without the need for ion-pair additives.