Proteomics

To better understand the functions of individual proteins and their place in complex biological systems, it’s necessary to measure changes in protein abundance relative to those of the system, and proteomics mass spectrometry makes that possible. Modern proteomics has shifted from its initial qualitative outlook to a continuum of qualitative and quantitative technologies and approaches which include state-of-the-art sample preparation, liquid chromatography separation, high-resolution, accurate-mass Thermo Scientific Orbitrap mass spectrometry, and proteomic software solutions for mass spectrometry data analysis.
We’re supporting successful laboratories in their discovery and study of proteomes as they combine these components into integrated workflows which maximize productivity and enable broader, deeper proteomic analysis. Our proven scientific network, publications, and pioneering solutions, driven by advances in Orbitrap mass spectrometry systems and consumables, are producing novel, stringent and reproducible results that are pushing proteomics research and discovery forward.

THERMO Scientific Orbitrap Exploris 240 mass spectrometer

Expand your capabilities from small- to large-scale studies across a variety of applications from protein identification, quantitation, to multiplexing proteomics studies. With optimized methods, the Thermo Scientific Orbitrap Exploris 240 mass spectrometer delivers a fast turnaround of sample to results with operational simplicity.

Go Beyond with leading performance and versatility

Expand your capabilities from small- to large-scale studies across a variety of applications from protein identification, quantitation, to multiplexing proteomics studies. With optimized methods, the Thermo Scientific Orbitrap Exploris 240 mass spectrometer delivers a fast turnaround of sample to results with operational simplicity.

Best-in-class performance, all within a compact footprint, so you can go beyond with everyday versatility.

Featured proteomics mass spectrometry categories

Learn more about our reagents, assays, kits and columns that enable robust and reproducible protein extraction from different samples, as well as peptide digestion, enrichment, and clean-up for mass spectrometry analysis.

Mass spectrometry calibration solutions are ready-to-use liquid formulations that can quickly calibrate LC-MS instrumentation. Validated standards are available for sensitivity assessment, determination of digestion efficiency, or as a control for complex sample analysis.

Analysis of proteomics experimental data ranges from mass spectra identification to quantitation to extraction of meaningful biological information. THERMO Scientific offers a suite of proteomics software products that enable you to quickly transform complex data into meaningful results.

Explore multiple products and workflows for protein structure analysis plus learn more about integrative structural biology solutions that bring together mass spectrometry and cryo-electron microscopy to solve large dynamic complexes.

Scientists are using our mass spectrometers and their robust, complementary products to go beyond identification to understanding how proteins act, interact and function under various conditions over time, creating impressive insights about complex biological systems.

Our workflows combine different biological sample processing kits with highly sensitive yet powerful instrumentation and integrated software platforms. This results in accurate and reproducible mass spectrometry data from targeted as well as untargeted analysis experiments.